This educational video demonstrates how to set up for an open reduction and internal fixation (ORIF) of tibial fractures. A comprehensive, detailed protocol for sterile field preparation, instrument organization, and supply arrangement is outlined, emphasizing the double-draping technique, strategic placement of orthopaedic instruments, and essential safety checks. The setup also covers the preparation of power drill systems, fixation hardware, irrigation equipment, and tourniquet supplies. This video serves as a practical and easy-to-follow guide for surgical technology students, new operating room personnel, and healthcare facilities working to develop consistent and safe orthopaedic trauma protocols.