Carotid stenosis is one of the leading causes of ischemic stroke worldwide. In the United States, nearly 800,000 strokes are reported each year, with ischemia accounting for 87% of them, and 15% traced to a carotid origin. Carotid endarterectomy represents an effective surgical treatment for carotid stenosis in preventing the risk of future ischemic stroke. In this video-article, we demonstrate the surgical technique for carotid endarterectomy on a cadaver and discuss a typical case presentation of an individual who could potentially benefit from this procedure.