This video demonstrates prophylactic ureteral stenting (PUS) and cystoscopy in a patient with advanced appendiceal cancer scheduled for combination of surgical cytoreduction and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC). It highlights the identification of ureteral orifices, stepwise stent placement, and bladder inspection. No resistance was encountered, and no abnormalities were observed. The stents were secured to prevent dislodgement. For selected patients, PUS offers a valuable strategy to reduce iatrogenic ureteral injury during high-risk procedures, with potential benefits outweighing associated risks when carefully considered.