This video provides a detailed step-by-step demonstration of thoracic epidural catheter placement at the T9–T10 level in preparation for cytoreductive surgery (CRS) and heated intraperitoneal chemotherapy (HIPEC). The procedure includes local anesthesia administration, needle advancement using loss-of-resistance technique, saline injection to expand the epidural space, catheter insertion, test dosing, and securement. Emphasis is placed on careful patient monitoring and tailored analgesia. Thoracic epidural anesthesia plays a critical role in perioperative management, offering improved pain control, reduced complications, and enhanced recovery outcomes in patients undergoing CRS and HIPEC.